BENCHMARK REPORT

Can I Run Qwen 2.5 32B Instruct on NVIDIA GeForce RTX 5080?

Comprehensive technical verdict based on static weights, dynamic KV Cache (8k baseline context window), and CUDA runtime overhead.

Official Verdict
NO — CUDA OOM

Executive Hardware Compatibility Summary: Qwen 2.5 32B Instruct on NVIDIA GeForce RTX 5080

Authoritative verdict, memory allocation, and token generation performance:

Direct Answer: CUDA OOM — Deficit of 7.7 GBQwen 2.5 32B Instruct exceeds dedicated physical VRAM and triggers PCIe layer offloading on NVIDIA GeForce RTX 5080 (16GB). At standard Q4_K_M 4-bit quantization and an 8,192-token context window, total memory demand is 23.75 GB (19.98 GB weights + 2.12 GB dynamic KV cache + 1.15 GB OS & CUDA buffers). Physical VRAM is exceeded by 7.75 GB, forcing 25 transformer layers to offload across the PCIe bus to host DDR RAM. Estimated generation throughput is ~10.1 tokens/sec (~99 ms per token) with prompt prefill processing reaching ~1428 tok/s.
Run Verdict
CUDA OOM (Offload)
Total Required VRAM
23.75 GB / 16 GB
Decoding Speed
~10.1 tok/s (99ms)
Safe Context Window
Offload to RAM

Hardware Architecture & VRAM Topology

Blackwell

NVIDIA GeForce RTX 5080 • 1024 GB/s Bandwidth

Token Generation
~10.1 tok/s(99 ms)
OOM SPILL
VRAM Utilization Breakdown23.75 GB / 16 GB (148%)
VRAM Limit (16G)
19.98G
2.12G
-7.75G Spill
Weights
19.98 GB
KV Cache
2.12 GB
Activation
0.5 GB
OS/Driver
1.15 GB
Overflow
7.75 GB
Hardware Chokepoint: PCIe Bus Throttling Active
GPU VRAM (16 GB)
39 / 64 Layers Loaded
1024 GB/s Bus
PCIe 4.0 x16 Bottleneck
31.5 GB/s
-97% Bandwidth Drop
Host DDR5 System RAM
25 Layers Offloaded
+9 GB RAM Siphoned

Why does your generation speed collapse to ~10.1 tok/s? Because for every single generated token, model weights across the 25 offloaded layers must be transferred across the 31.5 GB/s PCIe slot from host system RAM.

Context Window vs VRAM Scaling Curve

16G VRAM Limit2k22.16G4k22.69G8k23.75G16k25.87G32k30.11G64k38.59G128k55.55G0G16G
Blue line indicates total VRAM demand across context lengths; Red dashed line is physical VRAM ceiling.

CUDA OOM — Deficit of 7.7 GB

oom

25/64 layers will spill to CPU RAM, causing severe PCIe bandwidth throttling (est. 10.1 tok/s).

Throughput
~10.1 tok/s
99 ms / token
Headroom
-7.75 GB
148% of capacity
Layers Fit
39 / 64
25 on DDR5
Max Safe Ctx
0
Tokens before OOM
Host DDR RAM Status:Fits in DDR RAM (+9 GB used of 32 GB)
Static Permalink:/can-i-run/qwen-2-5-32b-instruct-on-rtx-5080
Open Static Report

Ready-to-Run CLI Commands

# Note: Model requires CPU offloading (39/64 layers on GPU)
ollama run qwen2.5:32b

Commands include automatic memory ceiling flags and model layer offload configurations calculated above.

Cloud Hardware Failover
gpuy.dev On-Demand Compute

Don't spend $2,000+ on hardware — Deploy Qwen 2.5 32B Instruct in 60s

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Launch Cloud Node →Pre-configured environment

Hardware Specification Summary

GPU ArchitectureBlackwell
Memory Bandwidth1024 GB/s
Model Parameters32.8B (LLM)
Attention ArchitectureGrouped-Query (GQA)
Prompt Prefill Speed~1428 tok/s (TTFT ~5737ms)
Benchmark Context Tested8,192 tokens
Customize in Full Matcher Simulator →

Global Compatibility Matrix for NVIDIA GeForce RTX 5080

Evaluated at Standard Q4_K_M Precision with 8,192 Tokens Context Window

Compatibility Index
61% (35/57)
33 Pass2 Tight22 OOM
Model & ArchitectureCategoryParametersRequired VRAMFit StatusEst. SpeedSimulate
DeepSeek-R1 (671B Full MoE)MLAMoE
DeepSeek
MoE671B(37B active)
411.16 GB
OOM (-395.16G)~0.7 tok/sSimulate
DeepSeek-V3 (671B Base/Chat)MLAMoE
DeepSeek
MoE671B(37B active)
411.16 GB
OOM (-395.16G)~0.7 tok/sSimulate
DeepSeek-R1-Distill-Llama-70B
DeepSeek
LLM70.6B
47.6 GB
OOM (-31.6G)~2.1 tok/sSimulate
DeepSeek-R1-Distill-Qwen-32B
DeepSeek
LLM32.8B
23.75 GB
OOM (-7.75G)~10.1 tok/sSimulate
DeepSeek-R1-Distill-Qwen-14B
DeepSeek
LLM14.7B
11.94 GB
100% VRAM Fit~80.1 tok/sSimulate
DeepSeek-R1-Distill-Llama-8B
DeepSeek
LLM8B
7.33 GB
100% VRAM Fit~147.1 tok/sSimulate
DeepSeek-R1-Distill-Qwen-8B
DeepSeek
LLM8.03B
7.48 GB
100% VRAM Fit~146.6 tok/sSimulate
DeepSeek-R1-Distill-Qwen-7B
DeepSeek
LLM7.6B
6.49 GB
100% VRAM Fit~154.9 tok/sSimulate
DeepSeek-R1-Distill-Qwen-1.5B
DeepSeek
LLM1.8B
2.61 GB
100% VRAM Fit~180 tok/sSimulate
DeepSeek-Coder-V2 Lite (16B / 2.4B MoE)MLAMoE
DeepSeek
MoE15.7B(2.4B active)
11.21 GB
100% VRAM Fit~180 tok/sSimulate
DeepSeek-Coder-V2 (236B / 21B MoE)MLAMoE
DeepSeek
MoE236B(21B active)
146.23 GB
OOM (-130.23G)~2.5 tok/sSimulate
Qwen 2.5 Coder 72B Instruct
Qwen
LLM72.7B
48.87 GB
OOM (-32.87G)~1.9 tok/sSimulate
Qwen 2.5 72B Instruct
Qwen
LLM72.7B
48.87 GB
OOM (-32.87G)~1.9 tok/sSimulate
Qwen 2.5 VL 72B (Vision Flagship)
Qwen
LLM72.7B
48.87 GB
OOM (-32.87G)~1.9 tok/sSimulate
Qwen 2.5 VL 7B (Vision)
Qwen
LLM7.61B
6.5 GB
100% VRAM Fit~154.7 tok/sSimulate
Qwen 2.5 Coder 32B Instruct
Qwen
LLM32.8B
23.75 GB
OOM (-7.75G)~10.1 tok/sSimulate
Qwen 2.5 Coder 14B Instruct
Qwen
LLM14.7B
11.94 GB
100% VRAM Fit~80.1 tok/sSimulate
Qwen 2.5 Coder 7B Instruct
Qwen
LLM7.6B
6.49 GB
100% VRAM Fit~154.9 tok/sSimulate
Qwen 2.5 Coder 1.5B Instruct
Qwen
LLM1.54B
2.45 GB
100% VRAM Fit~180 tok/sSimulate
Qwen 2.5 32B Instruct
Qwen
LLM32.8B
23.75 GB
OOM (-7.75G)~10.1 tok/sSimulate
Qwen 2.5 14B Instruct
Qwen
LLM14.7B
11.94 GB
100% VRAM Fit~80.1 tok/sSimulate
Qwen 2.5 7B Instruct
Qwen
LLM7.6B
6.49 GB
100% VRAM Fit~154.9 tok/sSimulate
Qwen 2.5 3B Instruct
Qwen
LLM3.1B
3.59 GB
100% VRAM Fit~180 tok/sSimulate
Qwen 2.5 0.5B Instruct
Qwen
LLM0.49B
1.8 GB
100% VRAM Fit~180 tok/sSimulate
Llama 3.3 70B Instruct
Llama
LLM70.6B
47.6 GB
OOM (-31.6G)~2.1 tok/sSimulate
Llama 3.1 70B Instruct
Llama
LLM70.6B
47.6 GB
OOM (-31.6G)~2.1 tok/sSimulate
Llama 3.1 405B Instruct
Llama
LLM405B
252.77 GB
OOM (-236.77G)~0.6 tok/sSimulate
Llama 3.1 8B Instruct
Llama
LLM8B
7.33 GB
100% VRAM Fit~147.1 tok/sSimulate
Llama 3.2 3B Instruct
Llama
LLM3.2B
4.28 GB
100% VRAM Fit~180 tok/sSimulate
Llama 3.2 1B Instruct
Llama
LLM1.23B
2.41 GB
100% VRAM Fit~180 tok/sSimulate
Llama 3.2 11B Vision Instruct
Llama
LLM10.6B
8.92 GB
100% VRAM Fit~111 tok/sSimulate
Llama 3.2 90B Vision Instruct
Llama
LLM89B
59.46 GB
OOM (-43.46G)~1.2 tok/sSimulate
Microsoft Phi-4 (14B)
Phi
LLM14.7B
12.01 GB
100% VRAM Fit~80.1 tok/sSimulate
Microsoft Phi-3.5 Mini (3.8B)
Phi
LLM3.82B
6.91 GB
100% VRAM Fit~180 tok/sSimulate
Google Gemma 2 9B Instruct
Gemma
LLM9.2B
9.79 GB
100% VRAM Fit~127.9 tok/sSimulate
Mistral Small 3 (24B Instruct)
Mistral
LLM24B
18.12 GB
OOM (-2.12G)~18.9 tok/sSimulate
Mistral NeMo (12B Instruct)
Mistral
LLM12.2B
10.15 GB
100% VRAM Fit~96.5 tok/sSimulate
Mistral 7B Instruct v0.3
Mistral
LLM7.25B
6.88 GB
100% VRAM Fit~162.3 tok/sSimulate
Codestral 22B (Mistral AI)
Mistral
LLM22.2B
17.02 GB
OOM (-1.02G)~22.1 tok/sSimulate
Mistral Large 2 (123B)
Mistral
LLM123B
79.77 GB
OOM (-63.77G)~0.7 tok/sSimulate
Mixtral 8x7B (MoE 47B)MoE
Mistral
MoE46.7B(12.9B active)
31.15 GB
OOM (-15.15G)~18.6 tok/sSimulate
Mixtral 8x22B (MoE 141B)MoE
Mistral
MoE141B(39B active)
89.67 GB
OOM (-73.67G)~1.9 tok/sSimulate
Pixtral 12B (Multimodal)
Mistral
LLM12.4B
10.28 GB
100% VRAM Fit~94.9 tok/sSimulate
Gemma 2 27B Instruct
Gemma
LLM27.2B
21.26 GB
OOM (-5.26G)~13.4 tok/sSimulate
Google Gemma 2 2B Instruct
Gemma
LLM2.6B
3.84 GB
100% VRAM Fit~180 tok/sSimulate
GLM-4 9B Chat (Zhipu AI)
GLM
LLM9.4B
7.79 GB
100% VRAM Fit~125.2 tok/sSimulate
FLUX.1 [dev] (12B DiT)
FLUX
ImageGen12B
15.68 GB
Tight Fit~98.1 tok/sSimulate
FLUX.1 [schnell] (4-step)
FLUX
ImageGen12B
15.68 GB
Tight Fit~98.1 tok/sSimulate
Stable Diffusion XL (SDXL 1.0)
SDXL
ImageGen3.5B
7.51 GB
100% VRAM Fit~180 tok/sSimulate
Stable Diffusion 1.5 (Classic)
SD
ImageGen1B
5.78 GB
100% VRAM Fit~180 tok/sSimulate
Whisper Large v3 (1.5B)
Whisper
Audio1.5B
3.64 GB
100% VRAM Fit~180 tok/sSimulate
Kokoro 82M (Text-to-Speech)
Kokoro
Audio0.082B
1.56 GB
100% VRAM Fit~180 tok/sSimulate
Wan2.1 (14B Text-to-Video)
Wan
ImageGen14.2B
18.72 GB
OOM (-2.72G)~30.4 tok/sSimulate
Wan2.1 (1.3B Video)
Wan
ImageGen1.3B
7.28 GB
100% VRAM Fit~180 tok/sSimulate
HunyuanVideo (13B Video DiT)
Hunyuan
ImageGen13B
19.69 GB
OOM (-3.69G)~30.4 tok/sSimulate
Stable Diffusion 3.5 Large (8B)
SD
ImageGen8.1B
13.3 GB
100% VRAM Fit~145.3 tok/sSimulate
BAAI BGE-M3 (Multilingual Embedding)
BAAI
LLM0.56B
2.54 GB
100% VRAM Fit~180 tok/sSimulate

Qwen 2.5 32B Instruct Context Scaling Matrix on NVIDIA GeForce RTX 5080

Dynamic KV Cache footprint and generation throughput measured across sequence lengths (Q4_K_M weights):

Context WindowKV Cache MemoryTotal VRAM DemandCompatibility StatusOffloaded LayersEst. Generation Speed
2,048 tokens (2k)0.53 GB22.16 GB / 16 GBCUDA OOM20 layers on RAM~11.4 tok/s
4,096 tokens (4k)1.06 GB22.69 GB / 16 GBCUDA OOM22 layers on RAM~10.9 tok/s
8,192 tokens (8k)Standard Baseline2.12 GB23.75 GB / 16 GBCUDA OOM25 layers on RAM~10.1 tok/s
16,384 tokens (16k)4.24 GB25.87 GB / 16 GBCUDA OOM32 layers on RAM~8.3 tok/s
32,768 tokens (32k)8.48 GB30.11 GB / 16 GBCUDA OOM46 layers on RAM~4.8 tok/s

Hardware Compatibility Q&A: Qwen 2.5 32B Instruct on NVIDIA GeForce RTX 5080

Technical answers for memory allocation, CUDA overhead, and execution parameters.

Can NVIDIA GeForce RTX 5080 run Qwen 2.5 32B Instruct?
CUDA OOM — Deficit of 7.7 GB. 25/64 layers will spill to CPU RAM, causing severe PCIe bandwidth throttling (est. 10.1 tok/s). At an 8k context window, total VRAM demand is 23.75 GB compared to NVIDIA GeForce RTX 5080's 16 GB frame buffer.
How much VRAM does Qwen 2.5 32B Instruct require?
At standard Q4_K_M quantization and 8k context, Qwen 2.5 32B Instruct requires approximately 23.75 GB of VRAM. This includes 19.98 GB for model weights, 2.12 GB for dynamic KV cache (Grouped-Query Attention (GQA)), 0.5 GB for activation buffers, and 1.15 GB for OS display and CUDA runtime overhead.
What generation speed (tokens/sec) can I expect on NVIDIA GeForce RTX 5080?
Estimated autoregressive token generation speed is ~10.1 tokens per second with a per-token latency of ~99 ms, powered by 1024 GB/s memory bandwidth. Prompt prefill processing reaches ~1428 tok/s (TTFT ~5737 ms).
What causes CUDA Out-of-Memory (OOM) when running Qwen 2.5 32B Instruct?
CUDA OOM occurs when total memory consumption exceeds NVIDIA GeForce RTX 5080's 16 GB physical VRAM. While model weights stay static, the KV cache grows with every conversation token. When VRAM fills up, inference engines (like Ollama or llama.cpp) must offload remaining layers across the PCIe bus (31.5 GB/s) to host system RAM, causing generation speed to drop sharply.
How do I run Qwen 2.5 32B Instruct locally on NVIDIA GeForce RTX 5080?
You can run Qwen 2.5 32B Instruct directly with Ollama using "ollama run qwen-2-5-32b-instruct". For advanced serving with vLLM or llama.cpp, copy the ready-to-run CLI commands in the CLI Commands section above with optimal context, quantization, and GPU layer offload parameters.

Related Hardware Benchmarks & Model Alternatives

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Recommended Alternative GPUs for Qwen 2.5 32B Instruct

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Other Popular Models You Can Run on NVIDIA GeForce RTX 5080

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Dual GPU Showdown: NVIDIA GeForce RTX 5080 vs NVIDIA GeForce RTX 4090

Compare memory bandwidth (1024 GB/s vs 1008 GB/s), VRAM headroom (16GB vs 24GB), and inference speed head-to-head.

Launch Showdown Arena

Frequently Asked Questions (FAQ)

Model weights are only one part of total VRAM consumption. When you prompt a model, the KV Cache (Key-Value Cache) stores all historical tokens. At 32k or 64k context, standard GQA attention can demand an additional 4GB to 12GB of VRAM! Combined with activation buffers and OS background consumption (0.8GB on Windows), total memory spikes beyond hardware capacity.