Can I Run Mistral NeMo (12B Instruct) on NVIDIA GeForce RTX 3080 (10GB)?
Comprehensive technical verdict based on static weights, dynamic KV Cache (8k baseline context window), and CUDA runtime overhead.
Executive Hardware Compatibility Summary: Mistral NeMo (12B Instruct) on NVIDIA GeForce RTX 3080 (10GB)
Authoritative verdict, memory allocation, and token generation performance:
Hardware Architecture & VRAM Topology
AmpereNVIDIA GeForce RTX 3080 (10GB) • 760 GB/s Bandwidth
Why does your generation speed collapse to ~31.9 tok/s? Because for every single generated token, model weights across the 1 offloaded layers must be transferred across the 31.5 GB/s PCIe slot from host system RAM.
Context Window vs VRAM Scaling Curve
CUDA OOM — Deficit of 0.2 GB
oom1/40 layers will spill to CPU RAM, causing severe PCIe bandwidth throttling (est. 31.9 tok/s).
/can-i-run/mistral-nemo-12b-on-rtx-3080-10gReady-to-Run CLI Commands
# Note: Model requires CPU offloading (39/40 layers on GPU)
ollama run mistral-nemo:12bCommands include automatic memory ceiling flags and model layer offload configurations calculated above.
Don't spend $2,000+ on hardware — Deploy Mistral NeMo (12B Instruct) in 60s
Your local NVIDIA GeForce RTX 3080 (10GB) is missing 0.15 GB of VRAM. Running on CPU RAM throttles speeds to ~31.9 tok/s. Spin up a cloud instance starting from $0.35/hr.
Hardware Specification Summary
Global Compatibility Matrix for NVIDIA GeForce RTX 3080 (10GB)
Evaluated at Standard Q4_K_M Precision with 8,192 Tokens Context Window
| Model & Architecture | Category | Parameters | Required VRAM | Fit Status | Est. Speed | Simulate |
|---|---|---|---|---|---|---|
DeepSeek-R1 (671B Full MoE)MLAMoE DeepSeek | MoE | 671B(37B active) | 411.16 GB | OOM (-401.16G) | ~0.6 tok/s | Simulate |
DeepSeek-V3 (671B Base/Chat)MLAMoE DeepSeek | MoE | 671B(37B active) | 411.16 GB | OOM (-401.16G) | ~0.6 tok/s | Simulate |
DeepSeek-R1-Distill-Llama-70B DeepSeek | LLM | 70.6B | 47.6 GB | OOM (-37.6G) | ~0.8 tok/s | Simulate |
DeepSeek-R1-Distill-Qwen-32B DeepSeek | LLM | 32.8B | 23.75 GB | OOM (-13.75G) | ~3.8 tok/s | Simulate |
DeepSeek-R1-Distill-Qwen-14B DeepSeek | LLM | 14.7B | 11.94 GB | OOM (-1.94G) | ~21.1 tok/s | Simulate |
DeepSeek-R1-Distill-Llama-8B DeepSeek | LLM | 8B | 7.33 GB | 100% VRAM Fit | ~109.2 tok/s | Simulate |
DeepSeek-R1-Distill-Qwen-8B DeepSeek | LLM | 8.03B | 7.48 GB | 100% VRAM Fit | ~108.8 tok/s | Simulate |
DeepSeek-R1-Distill-Qwen-7B DeepSeek | LLM | 7.6B | 6.49 GB | 100% VRAM Fit | ~114.9 tok/s | Simulate |
DeepSeek-R1-Distill-Qwen-1.5B DeepSeek | LLM | 1.8B | 2.61 GB | 100% VRAM Fit | ~180 tok/s | Simulate |
DeepSeek-Coder-V2 Lite (16B / 2.4B MoE)MLAMoE DeepSeek | MoE | 15.7B(2.4B active) | 11.21 GB | OOM (-1.21G) | ~142.3 tok/s | Simulate |
DeepSeek-Coder-V2 (236B / 21B MoE)MLAMoE DeepSeek | MoE | 236B(21B active) | 146.23 GB | OOM (-136.23G) | ~1.3 tok/s | Simulate |
Qwen 2.5 Coder 72B Instruct Qwen | LLM | 72.7B | 48.87 GB | OOM (-38.87G) | ~0.7 tok/s | Simulate |
Qwen 2.5 72B Instruct Qwen | LLM | 72.7B | 48.87 GB | OOM (-38.87G) | ~0.7 tok/s | Simulate |
Qwen 2.5 VL 72B (Vision Flagship) Qwen | LLM | 72.7B | 48.87 GB | OOM (-38.87G) | ~0.7 tok/s | Simulate |
Qwen 2.5 VL 7B (Vision) Qwen | LLM | 7.61B | 6.5 GB | 100% VRAM Fit | ~114.8 tok/s | Simulate |
Qwen 2.5 Coder 32B Instruct Qwen | LLM | 32.8B | 23.75 GB | OOM (-13.75G) | ~3.8 tok/s | Simulate |
Qwen 2.5 Coder 14B Instruct Qwen | LLM | 14.7B | 11.94 GB | OOM (-1.94G) | ~21.1 tok/s | Simulate |
Qwen 2.5 Coder 7B Instruct Qwen | LLM | 7.6B | 6.49 GB | 100% VRAM Fit | ~114.9 tok/s | Simulate |
Qwen 2.5 Coder 1.5B Instruct Qwen | LLM | 1.54B | 2.45 GB | 100% VRAM Fit | ~180 tok/s | Simulate |
Qwen 2.5 32B Instruct Qwen | LLM | 32.8B | 23.75 GB | OOM (-13.75G) | ~3.8 tok/s | Simulate |
Qwen 2.5 14B Instruct Qwen | LLM | 14.7B | 11.94 GB | OOM (-1.94G) | ~21.1 tok/s | Simulate |
Qwen 2.5 7B Instruct Qwen | LLM | 7.6B | 6.49 GB | 100% VRAM Fit | ~114.9 tok/s | Simulate |
Qwen 2.5 3B Instruct Qwen | LLM | 3.1B | 3.59 GB | 100% VRAM Fit | ~180 tok/s | Simulate |
Qwen 2.5 0.5B Instruct Qwen | LLM | 0.49B | 1.8 GB | 100% VRAM Fit | ~180 tok/s | Simulate |
Llama 3.3 70B Instruct Llama | LLM | 70.6B | 47.6 GB | OOM (-37.6G) | ~0.8 tok/s | Simulate |
Llama 3.1 70B Instruct Llama | LLM | 70.6B | 47.6 GB | OOM (-37.6G) | ~0.8 tok/s | Simulate |
Llama 3.1 405B Instruct Llama | LLM | 405B | 252.77 GB | OOM (-242.77G) | ~0.6 tok/s | Simulate |
Llama 3.1 8B Instruct Llama | LLM | 8B | 7.33 GB | 100% VRAM Fit | ~109.2 tok/s | Simulate |
Llama 3.2 3B Instruct Llama | LLM | 3.2B | 4.28 GB | 100% VRAM Fit | ~180 tok/s | Simulate |
Llama 3.2 1B Instruct Llama | LLM | 1.23B | 2.41 GB | 100% VRAM Fit | ~180 tok/s | Simulate |
Llama 3.2 11B Vision Instruct Llama | LLM | 10.6B | 8.92 GB | Tight Fit | ~82.4 tok/s | Simulate |
Llama 3.2 90B Vision Instruct Llama | LLM | 89B | 59.46 GB | OOM (-49.46G) | ~0.6 tok/s | Simulate |
Microsoft Phi-4 (14B) Phi | LLM | 14.7B | 12.01 GB | OOM (-2.01G) | ~21.2 tok/s | Simulate |
Microsoft Phi-3.5 Mini (3.8B) Phi | LLM | 3.82B | 6.91 GB | 100% VRAM Fit | ~180 tok/s | Simulate |
Google Gemma 2 9B Instruct Gemma | LLM | 9.2B | 9.79 GB | Tight Fit | ~95 tok/s | Simulate |
Mistral Small 3 (24B Instruct) Mistral | LLM | 24B | 18.12 GB | OOM (-8.12G) | ~7.3 tok/s | Simulate |
Mistral NeMo (12B Instruct) Mistral | LLM | 12.2B | 10.15 GB | OOM (-0.15G) | ~31.9 tok/s | Simulate |
Mistral 7B Instruct v0.3 Mistral | LLM | 7.25B | 6.88 GB | 100% VRAM Fit | ~120.5 tok/s | Simulate |
Codestral 22B (Mistral AI) Mistral | LLM | 22.2B | 17.02 GB | OOM (-7.02G) | ~8.6 tok/s | Simulate |
Mistral Large 2 (123B) Mistral | LLM | 123B | 79.77 GB | OOM (-69.77G) | ~0.6 tok/s | Simulate |
Mixtral 8x7B (MoE 47B)MoE Mistral | MoE | 46.7B(12.9B active) | 31.15 GB | OOM (-21.15G) | ~8.2 tok/s | Simulate |
Mixtral 8x22B (MoE 141B)MoE Mistral | MoE | 141B(39B active) | 89.67 GB | OOM (-79.67G) | ~0.9 tok/s | Simulate |
Pixtral 12B (Multimodal) Mistral | LLM | 12.4B | 10.28 GB | OOM (-0.28G) | ~30.6 tok/s | Simulate |
Gemma 2 27B Instruct Gemma | LLM | 27.2B | 21.26 GB | OOM (-11.26G) | ~4.7 tok/s | Simulate |
Google Gemma 2 2B Instruct Gemma | LLM | 2.6B | 3.84 GB | 100% VRAM Fit | ~180 tok/s | Simulate |
GLM-4 9B Chat (Zhipu AI) GLM | LLM | 9.4B | 7.79 GB | 100% VRAM Fit | ~92.9 tok/s | Simulate |
FLUX.1 [dev] (12B DiT) FLUX | ImageGen | 12B | 15.68 GB | OOM (-5.68G) | ~15.6 tok/s | Simulate |
FLUX.1 [schnell] (4-step) FLUX | ImageGen | 12B | 15.68 GB | OOM (-5.68G) | ~15.6 tok/s | Simulate |
Stable Diffusion XL (SDXL 1.0) SDXL | ImageGen | 3.5B | 7.51 GB | 100% VRAM Fit | ~180 tok/s | Simulate |
Stable Diffusion 1.5 (Classic) SD | ImageGen | 1B | 5.78 GB | 100% VRAM Fit | ~180 tok/s | Simulate |
Whisper Large v3 (1.5B) Whisper | Audio | 1.5B | 3.64 GB | 100% VRAM Fit | ~180 tok/s | Simulate |
Kokoro 82M (Text-to-Speech) Kokoro | Audio | 0.082B | 1.56 GB | 100% VRAM Fit | ~180 tok/s | Simulate |
Wan2.1 (14B Text-to-Video) Wan | ImageGen | 14.2B | 18.72 GB | OOM (-8.72G) | ~10.2 tok/s | Simulate |
Wan2.1 (1.3B Video) Wan | ImageGen | 1.3B | 7.28 GB | 100% VRAM Fit | ~180 tok/s | Simulate |
HunyuanVideo (13B Video DiT) Hunyuan | ImageGen | 13B | 19.69 GB | OOM (-9.69G) | ~10.7 tok/s | Simulate |
Stable Diffusion 3.5 Large (8B) SD | ImageGen | 8.1B | 13.3 GB | OOM (-3.3G) | ~29 tok/s | Simulate |
BAAI BGE-M3 (Multilingual Embedding) BAAI | LLM | 0.56B | 2.54 GB | 100% VRAM Fit | ~180 tok/s | Simulate |
Mistral NeMo (12B Instruct) Context Scaling Matrix on NVIDIA GeForce RTX 3080 (10GB)
Dynamic KV Cache footprint and generation throughput measured across sequence lengths (Q4_K_M weights):
| Context Window | KV Cache Memory | Total VRAM Demand | Compatibility Status | Offloaded Layers | Est. Generation Speed |
|---|---|---|---|---|---|
| 2,048 tokens (2k) | 0.33 GB | 9.16 GB / 10 GB | Tight Headroom | 0 (All in VRAM) | ~71.6 tok/s |
| 4,096 tokens (4k) | 0.66 GB | 9.49 GB / 10 GB | Tight Headroom | 0 (All in VRAM) | ~71.6 tok/s |
| 8,192 tokens (8k)Standard Baseline | 1.33 GB | 10.15 GB / 10 GB | CUDA OOM | 1 layers on RAM | ~31.9 tok/s |
| 16,384 tokens (16k) | 2.65 GB | 11.48 GB / 10 GB | CUDA OOM | 8 layers on RAM | ~26.3 tok/s |
| 32,768 tokens (32k) | 5.30 GB | 14.13 GB / 10 GB | CUDA OOM | 23 layers on RAM | ~14.3 tok/s |
Hardware Compatibility Q&A: Mistral NeMo (12B Instruct) on NVIDIA GeForce RTX 3080 (10GB)
Technical answers for memory allocation, CUDA overhead, and execution parameters.
Can NVIDIA GeForce RTX 3080 (10GB) run Mistral NeMo (12B Instruct)?
How much VRAM does Mistral NeMo (12B Instruct) require?
What generation speed (tokens/sec) can I expect on NVIDIA GeForce RTX 3080 (10GB)?
What causes CUDA Out-of-Memory (OOM) when running Mistral NeMo (12B Instruct)?
How do I run Mistral NeMo (12B Instruct) locally on NVIDIA GeForce RTX 3080 (10GB)?
Related Hardware Benchmarks & Model Alternatives
Compare Mistral NeMo (12B Instruct) and NVIDIA GeForce RTX 3080 (10GB) against alternative configurations:
Recommended Alternative GPUs for Mistral NeMo (12B Instruct)
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Other Popular Models You Can Run on NVIDIA GeForce RTX 3080 (10GB)
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Dual GPU Showdown: NVIDIA GeForce RTX 3080 (10GB) vs NVIDIA GeForce RTX 4090
Compare memory bandwidth (760 GB/s vs 1008 GB/s), VRAM headroom (10GB vs 24GB), and inference speed head-to-head.
Frequently Asked Questions (FAQ)
Model weights are only one part of total VRAM consumption. When you prompt a model, the KV Cache (Key-Value Cache) stores all historical tokens. At 32k or 64k context, standard GQA attention can demand an additional 4GB to 12GB of VRAM! Combined with activation buffers and OS background consumption (0.8GB on Windows), total memory spikes beyond hardware capacity.